Postseason

Round	Result	Games
Wild Card	Boston Red Sox 1–0 New York Yankees	1
Wild Card	Los Angeles Dodgers 1–0 St. Louis Cardinals	1
Division Series	Boston Red Sox 3–1 Tampa Bay Rays	4
Division Series	Houston Astros 3–1 Chicago White Sox	4
Division Series	Atlanta Braves 3–1 Milwaukee Brewers	4
Division Series	Los Angeles Dodgers 3–2 San Francisco Giants	5
League Championship	Houston Astros 4–2 Boston Red Sox	6
League Championship	Atlanta Braves 4–2 Los Angeles Dodgers	6
World Series	Atlanta Braves 4–2 Houston Astros	6

AL Central

#	Team	W	L	Pct	GB	RA	Attendance	Manager
1	Chicago White Sox	93	69	.574	—	636	1,596,385	Tony LaRussa, Miguel Cairo	Division
2	Cleveland Indians	80	82	.494	13	727	1,114,368	Terry Francona, DeMarlo Hale
3	Detroit Tigers	77	85	.475	16	756	1,102,621	A. J. Hinch
4	Kansas City Royals	74	88	.457	19	788	1,159,613	Mike Matheny
5	Minnesota Twins	73	89	.451	20	834	1,310,199	Rocco Baldelli, Bill Evers

AL East

#	Team	W	L	Pct	GB	RA	Attendance	Manager
1	Tampa Bay Rays	100	62	.617	—	651	761,072	Kevin Cash	Division
2	Boston Red Sox	92	70	.568	8	749	1,725,323	Alex Cora	Wild Card
2	New York Yankees	92	70	.568	8	669	1,959,854	Aaron Boone	Wild Card
4	Toronto Blue Jays	91	71	.562	9	663	805,901	Charlie Montoyo, John Schneider
5	Baltimore Orioles	52	110	.321	48	956	793,229	Brandon Hyde

AL West

#	Team	W	L	Pct	GB	RA	Attendance	Manager
1	Houston Astros	95	67	.586	—	658	2,068,509	Dusty Baker	Pennant Division
2	Seattle Mariners	90	72	.556	5	748	1,215,985	Scott Servais
3	Oakland Athletics	86	76	.531	9	687	701,430	Bob Melvin
4	Los Angeles Angels of Anaheim	77	85	.475	18	804	1,515,689	Joe Maddon
5	Texas Rangers	60	102	.370	35	815	2,110,258	Chris Woodward

NL Central

#	Team	W	L	Pct	GB	RA	Attendance	Manager
1	Milwaukee Brewers	95	67	.586	—	623	1,824,282	Craig Counsell	Division
2	St. Louis Cardinals	90	72	.556	5	672	2,102,530	Mike Shildt	Wild Card
3	Cincinnati Reds	83	79	.512	12	760	1,505,024	David Bell
4	Chicago Cubs	71	91	.438	24	839	1,978,934	David Ross, Andy Green
5	Pittsburgh Pirates	61	101	.377	34	833	859,498	Derek Shelton

NL East

#	Team	W	L	Pct	GB	RA	Attendance	Manager
1	Atlanta Braves	88	73	.547	—	656	2,300,247	Brian Snitker	World Series Division
2	Philadelphia Phillies	82	80	.506	6.5	745	1,515,890	Joe Girardi
3	New York Mets	77	85	.475	11.5	668	1,511,926	Luis Rojas, Dave Jauss
4	Miami Marlins	67	95	.414	21.5	701	642,617	Don Mattingly, James Rowson
5	Washington Nationals	65	97	.401	23.5	820	1,465,543	Dave Martinez

NL West

#	Team	W	L	Pct	GB	RA	Attendance	Manager
1	San Francisco Giants	107	55	.660	—	594	1,679,484	Gabe Kapler	Division
2	Los Angeles Dodgers	106	56	.654	1	561	2,804,693	Dave Roberts	Wild Card
3	San Diego Padres	79	83	.488	28	708	2,191,950	Jayce Tingler
4	Colorado Rockies	74	87	.460	32.5	796	1,938,645	Buddy Black
5	Arizona Diamondbacks	52	110	.321	55	893	1,043,010	Torey Lovullo

Leaders

AL

NL

No-hitters

• Joe Musgrove, San Diego Padres vs. Texas Rangers, 2021-04-09
• Carlos Rodon, Chicago White Sox vs. Cleveland Indians, 2021-04-14
• John Means, Baltimore Orioles vs. Seattle Mariners, 2021-05-05
• Wade Miley, Cincinnati Reds vs. Cleveland Indians, 2021-05-07
• Spencer Turnbull, Detroit Tigers vs. Seattle Mariners, 2021-05-18
• Corey Kluber, New York Yankees vs. Texas Rangers, 2021-05-19
• Tyler Gilbert, Arizona Diamondbacks vs. San Diego Padres, 2021-08-14